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. 2022 Dec 20;13:1090324. doi: 10.3389/fendo.2022.1090324

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Copyright © 2022 Shi, Wang, Yang, Zhang, Zhang, Feng, Lv, Niu, Chen, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of functional enrichment and application of the signature in drug sensitivity. (A) The GO analysis by a chordal graph. (B) The KEGG analysis between low- and high-risk groups by a chordal graph. (C) The hallmark processes by GSVA analysis in five genes by GSVA analysis. (D) The KEGG signaling pathway by GSVA analysis. The association between drug sensitivity and low- and high-risk groups: (E) Doxorubicin. (F) Bleomycin. (G) Gemcitabine. (H) Bortezomib. (I) Imatinib. (J) Paclitaxel. (K) Methotrexate. (L) Rapamycin. (M) Sorafenib. (N) Vorinostat. (O) AKT.inhibitor VIII. (P) Axitinib.