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. 2022 Dec 17;17:100222. doi: 10.1016/j.metop.2022.100222

Table 2.

Effects of aqueous root extracts of E. racemose L. on GI transit in loperamide induced constipated mice.

Groups Weight of the animal Distance traveled by charcoal (cm) P-value against NOC P-value against NC GI transit ratio (%) P-value against NOC P-value against NC
NOC 24.8 ± 0.66 16.6 ± 3.51 0.20 36.19 ± 1.73 0.47
NC 22.75 ± 0.54 7.80 ± 1.11 0.20 15.07 ± 2.32 0.47
BIS0.25 24.8 ± 0.86 27.36 ± 0.26b3 0.72 0.00 89.562 ± 0 3.34a2b3 0.001 0.00
ERAE100 26.0 ± 2.02 28.80 ± 2.39a2b3 0.03 0.00 66.51 ± 16.73b2 0.1313 0.00
ERAE200 32.20 ± 1.46 30.40 ± 4.36a2b3 0.01 0.00 79.82 ± 9.99a1b3 0.01 0.00
ERAE400 24.7 ± 1.06 32.56 ± 1.54a3b3 0.01 0.00 92.95 ± 2.28a3b3 0.001 0.00

Each value represents mean ± S.E.M; n = 5 for each treatment; Analysis was performed by one way ANOVA; a, compared to normal control; b, compared to negative control; NOC, normal control; NC, negative control; ERAE, E. racemosa L. aqueous extract; number followed by ERAE and BIS indicates dose in mg/kg. 1p < 0.05; 2p < 0.01; 3p < 0.001.