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. 2022 Dec 20;13:1017780. doi: 10.3389/fimmu.2022.1017780

Figure 6.

Figure 6

Salmonella treatment increases the percentages of splenic CD4+ T cells and Ly6G+ neutrophils in MC38-tumor bearing mice. Tumor-bearing mice were treated with ~5× 103 CFUs of Salmonella on day 7 post tumor implantation. Mice were sacrificed on day 14 post bacterial treatment and spleens were collected for flow cytometric analysis. Representative dot plots and the percentage of T cells (A, B), B cells (A, C), CD4+ T cells (D, E), CD8+ T cells (D, F), CD11b+ myeloid cells (G, H), neutrophils (Ly6G+) (I, J) and monocytes/macrophages (Ly6G- F4/80+) (I, K) are illustrated. The percentage of macrophages that express MHC class II was also determined (L, M). The expression of MHC II on monocytes/macrophages was evaluated (N). Each data point represents a single mouse, pooled from two independent experiments. Asterisks denote statistically significant differences from control group, * (P ≤ 0.05), ** (P ≤ 0.01), **** (P ≤ 0.0001) and ns (no statistical significance, ≥ 0.05).