Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 20;12:1049065. doi: 10.3389/fcimb.2022.1049065

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Healer, Thompson, Mackwell, Browne, Seager, Ngo, Lowes, Silk, Pulido, King, Christen, Noe, Kotraiah, Masendycz, Rajagopalan, Lucas, Stanford, Soisson, Diggs, Miller, Youll, Wycherley, Draper and Cowman

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Functional activity is not correlated with immunogenicity in RCR multiple antigen combination immunisations. (A) Antibody reactivity in terminal bleed sera from individual rats was tested in ELISA against individual antigen components and the results are shown as OD1 titers calculated from 4PL curve fits based on the dilution curves of individual samples. Circles represent the OD1 titer from an individual rat serum titration and bars show the median of the six serum OD1 values. (B) GIA in IgG purified from individual rat sera. Bars show mean % GIA in each cohort of 6 rats at an IgG concentration of 2 mg/mL. Error bars show SEM.