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. 2022 Nov 24;299(1):102746. doi: 10.1016/j.jbc.2022.102746

Figure 2.

Figure 2

H&E staining of skin raft cultures treated with rexinoid agonists. (A) DMSO, solvent control, human organotypic skin raft cultures were treated with rexinoid agonists: (B) 0.2 μM Targretin, (C) 0.2 μM UAB30, (D) 10 μM UAB30, (E) 0.2 μM UAB110, and (F) 0.2 μM UAB111. The rexinoids were added to the culture medium at the onset of organotypic skin raft formation, and the rafts were allowed to grow for 11 days. Colored lines at the left side of each panel demarcate the layers of the epidermis: cornified (red), granular (blue), spinous (green), and basal (black).