Table 1.
Summary of studies reporting the association between glaucoma and NPS
| First author (year) | Study design | NPS cases, n | Glaucoma diagnosis, n | Type of glaucoma | Age of diagnosis |
|---|---|---|---|---|---|
| Lichter et al. [3] (1997) | Case series | Family 1: 13 Family 2: 11 |
6 7 |
GL: 6 GL: 5 PG: 1 PDS: 1 |
Mean age family 1: 32 yo Mean age family 2: 24 yo (2 cases of congenital glaucoma) |
| Fröhlich et al. [9] (2002) | Case report | 2 | 1 | OAG | 42 |
| Sweeney [1] (2003) | Case series | 83 | 14 | GL: 8 OHT: 6 |
Mean age: 47.9 years (23–78 years) |
| Bongers [2] (2005) | Case series | 51 | 17 | OAG: 2 NTG: 4 OHT: 2 GL: 9 |
Mean age: 63.4 yo 1 case of OAG <40 yo 1 case of OHT <40 yo |
| Mimiwati et al. [4] (2006) | Case series | 19 | 4 | OAG: 1 NTG: 1 OHT: 2 |
33 63 14–24 |
| Millá et al. [5] (2017) | Case series | 10 | 7 | OAG: 1 OHT: 6 |
|
| Romero et al. [6] (2011) | Case series | 5 | 4 | GL: 3 OHT: 1 |
57–53–42 21 |
| Ghoumid et al. [7] (2016) | Case series | 43 | 9 | GL: 9 | 5 of them <40 yo |
| Nicolle et al. [8] (2017) | Case report | 1 | 1 | OAG | About 35 yo |
| Gardin et al. [10] (2020) | Case report | 1 | 1 | Plateau iris syndrome and angle-closure glaucoma | 32 yo |
| Total | 239 (only case series) | 71 (29.7%) |
Only cases reporting an eye examination were included. GL, glaucoma; NL, normal; NPS, nail-patella syndrome; OHT, ocular hypertension; NTG, normal tension glaucoma; OAG, open-angle glaucoma; PG, pigmentary glaucoma; PDS, pigment dispersion syndrome; IOP, intraocular pressure; yo, years old.