Table 2.
Clinical characteristics and analysis of influencing factors for severe prolonged jaundice (TSB ≥ 342 µmol/L).
| Clinical characteristics | Group1 (n = 107) (TSB < 342 µmol/L) | Group2 (n = 68) (TSB ≥ 342 µmol/L) | P-value | Adjusted OR (95% CI) | P-value |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 71 (66.4) | 40 (58.8) | 0.313 | reference | NA |
| Female | 36 (33.6) | 28 (41.2) | 1.67 (0.99–2.82) | 0.056 | |
| Age (days) | 20.96 ± 7.70 | 18.78 ± 7.70 | 0.065 | 0.97 (0.35–2.74) | 0.956 |
| Birth weight (kg) | 3.11 ± 0.35 | 3.24 ± 0.50 | 0.058 | 0.96 (0.83–1.11) | 0.535 |
| Gestational age (weeks) | 38.75 ± 1.50 | 38.69 ± 1.17 | 0.786 | 1.00 (0.98–1.01) | 0.782 |
| Delivery mode | |||||
| Vaginal | 73 (68.2) | 42 (61.8) | 0.380 | reference | NA |
| Cesarean | 34 (31.8) | 26 (38.2) | 1.29 (0.64–2.62) | 0.474 | |
| Phototherapy | 52 (48.5) | 68 (100.0) | <0.001 | NA | NA |
| Feeding | |||||
| Formula feeding | 26 (24.3) | 15 (22.1) | 0.940 | reference | NA |
| Breast feeding | 51 (47.7) | 33 (48.5) | 0.67 (0.28–1.60) | 0.366 | |
| Mix feeding | 30 (28.0) | 20 (29.4) | 0.86 (0.39–1.92) | 0.714 | |
| MaximumTSB (µmol/L) | 196.0 (149.9–249.4) | 398.3 (352.0–445.2) | <0.001 | NA | NA |
| G6PD deficiency | 3 (2.8) | 3 (4.4) | 0.679 | 1.35 (0.22–0.85) | 0.748 |
| UGT1A1*6 (c.211G > A) | |||||
| G/G | 58 (54.2) | 14 (20.6) | <0.001 | reference | NA |
| G/A | 42 (39.3) | 40 (58.8) | 4.01 (1.91–8.45) | <0.001 | |
| A/A | 7 (6.5) | 14 (20.6) | 8.80 (2.84–27.23) | <0.001 | |
Data are presented as n (%), mean ± standard deviation, or median (95% Confidence Interval).
NA, not applicable; OR, odds ratio.