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Summary of the dose-escalation part. Representation of the dose-escalation part of the MOVIE study. Starting dose of MVino was 30 mg 3QW (dose level 1). The next dose level was 40 mg 3QW (dose level 2). Three patients were initially included at each dose level. In the absence of DLTs, dose level 2 was opened for inclusion and then extended to include a total of nine assessable patients.
DLT, dose-limiting toxicity.
