Table 2.

Binding of the ACE2 protein receptor by RBD of SARS‐CoV‐2, after dialysis of both binding partners in TRIS buffer containing 1 mm Zn²⁺ (left column) and without Zn²⁺ (right column), at pH 7.4 and 25 °C.

	ACE2 – RBDCoV2b (buffer with Zn2+ ions)	ACE2 – RBDCoV2b (buffer without Zn2+ ions)
K dITC (nm)	17.9 ± 9.4	15.9 ± 2.3
ΔH ITC (kcal·mol−1)	−15.2 ± 0.8	−22.15 ± 0.25
N ITC	0.79 ± 0.01	0.83 ± 0.04
−T Δ S ITC (kcal·mol−1)	4.61	11.4