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. 2023 Jan 3;2023(1):CD011881. doi: 10.1002/14651858.CD011881.pub2
Source Search strategy Hits retrieved
CDCIG Register (crsweb.cochrane.org/login.html)
[Date of most recent search: 13 January 2022]
(SLE OR sleep* OR circadian OR nocturnal OR insomnia* OR hypersomnia or parasomnia) AND (RCT OR CCT) AND (non‐pharmacological) Jul 2011:
Jun 2015: 237
Mar 2016: 3
Nov 2016: 0
Jan 2018: 2
Dec 2018: 9
Dec 2019: 13
Oct 2020: 6
Jan 2022: 20
MEDLINE In‐process and other non‐indexed citations and MEDLINE 1946‐present (OvidSP)
[Date of most recent search: 13 January 2022]
1. exp Dementia/
2. Delirium/
3. Wernicke Encephalopathy/
4. Delirium, Dementia, Amnestic, Cognitive Disorders/
5. dement*.mp.
6. alzheimer*.mp.
7. (lewy* adj2 bod*).mp.
8. deliri*.mp.
9. (chronic adj2 cerebrovascular).mp.
10. ("organic brain disease" or "organic brain syndrome").mp.
11. ("normal pressure hydrocephalus" and "shunt*").mp.
12. "benign senescent forgetfulness".mp.
13. (cerebr* adj2 deteriorat*).mp.
14. (cerebral* adj2 insufficient*).mp.
15. (pick* adj2 disease).mp.
16. (creutzfeldt or jcd or cjd).mp.
17. huntington*.mp.
18. binswanger*.mp.
19. korsako*.mp.
20. "cognit* impair*".mp.
21. neurodegenerat*.mp.
22. cerebrovascular.mp.
23. neuropsychiatric.mp.
24. neurobehavioral.mp.
25. or/1‐24
26. exp Sleep/
27. sleep*.ti,ab.
28. "Sleep Initiation and Maintenance Disorders"/
29. insomnia.mp.
30. exp sleep disorders, circadian rhythm/ or "disorders of excessive somnolence"/
31. (hypersomnia or parasomnia).mp.
32. circadian.mp.
33. or/26‐32
34. 25 and 33
35. randomized controlled trial.pt.
36. controlled clinical trial.pt.
37. randomized.ab.
38. placebo.ab.
39. drug therapy.fs.
40. randomly.ab.
41. trial.ab.
42. groups.ab.
43. or/35‐42
44. (animals not (humans and animals)).sh.
45. 43 not 44
46. 34 and 45
Jul 2011:
Jun 2015: 94
Mar 2016: 232
Nov 2016: 185
Jan 2018: 463
Dec 2018: 198
Dec 2019: 463
Oct 2020: 466
Jan 2022: 758
Embase (OvidSP)
1974‐present
[Date of most recent search: 13 January 2022]
1. exp Dementia/
2. dement*.mp.
3. alzheimer*.mp.
4. (lewy* adj2 bod*).mp.
5. (chronic adj2 cerebrovascular).mp.
6. ("organic brain disease" or "organic brain syndrome").mp.
7. (cerebr* adj2 deteriorat*).mp.
8. (cerebral* adj2 insufficient*).mp.
9. (pick* adj2 disease).mp.
10. (creutzfeldt or jcd or cjd).mp.
11. huntington*.mp.
12. binswanger*.mp.
13. korsako*.mp.
14. or/1‐13
15. exp Sleep/
16. sleep*.ti,ab.
17. sleep disorder/
18. insomnia.mp.
19. circadian rhythm/ or circadian rhythm sleep disorder/
20. circadian.mp.
21. (hypersomnia or parasomnia).mp.
22. somnolence/
23. somnolence.mp.
24. or/15‐23
25. randomized controlled trial/
26. controlled clinical trial/
27. randomly.ab.
28. randomi?ed.ab.
29. groups.ab.
30. RCT.ti,ab.
31. "double‐blind*".ti,ab.
32. "single blind*".ti,ab.
33. placebo.ab.
34. randomi?ed.ti.
35. or/25‐34
Jul 2011:
Jun 2015: 134
Mar 2016: 815
Nov 2016: 213
Jan 2018: 487
Dec 2018: 431
Dec 2019: 552
Oct 2020: 468
Jan 2022: 569
PSYCINFO
1806‐present (OvidSP)
[Date of most recent search: 13 January 2022]
1. exp Dementia/
2. dement*.mp.
3. alzheimer*.mp.
4. (lewy* adj2 bod*).mp.
5. (chronic adj2 cerebrovascular).mp.
6. ("organic brain disease" or "organic brain syndrome").mp.
7. (cerebr* adj2 deteriorat*).mp.
8. (cerebral* adj2 insufficient*).mp.
9. (pick* adj2 disease).mp.
10. (creutzfeldt or jcd or cjd).mp.
11. huntington*.mp.
12. binswanger*.mp.
13. korsako*.mp.
14. or/1‐13
15. exp Sleep Treatment/ or exp Sleep/ or exp Sleep Disorders/
16. sleep*.ti,ab.
17. insomnia.mp.
18. exp Sleep Wake Cycle/
19. circadian.mp.
20. (hypersomnia or parasomnia).mp.
21. exp Hypersomnia/
22. somnolence.mp.
23. or/15‐22
24. exp Clinical Trials/
25. randomly.ab.
26. randomi?ed.ab.
27. groups.ab.
28. RCT.ti,ab.
29. "double‐blind*".ti,ab.
30. "single blind*".ti,ab.
31. placebo.ab.
32. randomi?ed.ti.
33. or/24‐32
34. 14 and 23 and 33
Jul 2011:
Jun 2015: 19
Mar 2016: 45
Nov 2016: 30
Jan 2018: 77
Dec 2018: 30
Dec 2019: 72
Oct 2020: 67
Jan 2022: 92
CINAHL (EBSCOhost)
[Date of most recent search: 13 January 2022]
  Jul 2011:
Jun 2015: 12
Mar 2016: 45
Nov 2016: 19
Jan 2018: 85
Dec 2018: 129
Dec 2019: 231
Oct 2020: 198
Jan 2022: 238
Web of Science – all databases (Clarivate)
[Date of most recent search: 13 January 2022
(dement* OR alzheimer* OR AD OR VCI OR VaD OR "vascular cognitive impairment" OR "lew* bod*" OR CADASIL) ANDTOPIC: (sleep* OR circadian* OR insomnia* OR hypersomnia OR parasomnia OR somnolence) ANDTOPIC: (randomized OR randomised OR randomly OR "random allocat*" OR RCT OR "double‐blind*" OR "single‐blind*")
Timespan: All years.
Search language=Auto
Jul 2011:
Jun 2015: 31
Mar 2016: 109
Nov 2016: 83
Jan 2018: 206
Dec 2018: 89
Dec 2019: 175
Oct 2020: 162
Jan 2022: 217
LILACS (BIREME)
[Date of most recent search: 13 January 2022]
dementia OR demencia OR alzheimer$ [Words] and sleep OR insomnia OR circadian OR hypersomnia OR parasomnia OR sueño OR dorme [Words] and randomised OR randomized OR trial OR randomly OR groups [Words] Jul 2011:
Jun 2015: 0
Mar 2016: 0
Nov 2016: 0
Jan 2018: 0
Dec 2018: 0
Dec 2019: 0
Oct 2020: 12
Jan 2022: 0
CENTRAL (the Cochrane Library)
[Date of most recent search: 13 January 2022]
#1 MeSH descriptor: [Dementia] explode all trees
#2 dement*
#3 alzheimer*
#4 lewy* near/2 bod*
#5 chronic near/2 cerebrovascular
#6 "organic brain disease" or "organic brain syndrome"
#7 cerebr* near/2 deteriorat*
#8 cerebral* near/2 insufficient*
#9 pick* near/2 disease
#10 creutzfeldt or jcd or cjd
#11 huntington*
#12 binswanger*
#13 korsako*
#14 #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13
#15 sleep*
#16 insomnia*
#17 circadian
#18 hypersomnia
#19 parasomnia
#20 MeSH descriptor: [Sleep] explode all trees
#21 #15 or #16 or #17 or #18 or #19 or #20
#22 #14 and #21
Jul 2011:
Jun 2015: 4
Mar 2016: 39
Nov 2016: 18
Jan 2018: 148
Dec 2018: 132
Dec 2019: 392
Oct 2020: 120
Jan 2022: 255
ClinicalTrials.gov (www.clinicaltrials.gov)
[Date of most recent search: 13 January 2022]
sleep OR circadian OR nocturnal OR insomnia OR hypersomnia OR parasomnia | Interventional Studies | dementia OR alzheimers OR alzheimer OR lewy OR “vascular cognitive impairment”
[Recruitment status: all]
Jul 2011:
Jun 2015: 4
Mar 2016: 27
Nov 2016: 2
Jan 2018: 8
Dec 2018: 33
Dec 2019: 92
Oct 2020: 92
Jan 2022: 117
ICTRP Search Portal (apps.who.int/trialsearch) [includes: Australian New Zealand Clinical Trials Registry; ClinicalTrials.gov; ISRCTN; Chinese Clinical Trial Registry; Clinical Trials Registry – India; Clinical Research Information Service – Republic of Korea; German Clinical Trials Register; Iranian Registry of Clinical Trials; Japan Primary Registries Network; Pan African Clinical Trial Registry; Sri Lanka Clinical Trials Registry; The Netherlands National Trial Register]
[Date of most recent search: 13 January 2022]
sleep OR circadian OR nocturnal OR insomnia OR hypersomnia OR parasomnia | Interventional Studies | dementia OR alzheimers OR Alzheimer OR lewy OR “vascular cognitive impairment”
[Recruitment status: all]
Jul 2011:
Jun 2015: 0
Mar 2016: 40
Nov 2016: 5
Jan 2018: 5
Dec 2018: 2
Dec 2019: 22
Oct 2020: n/a
Jan 2022: 15
TOTAL before deduplication Jul 2011: 415
Jun 2015: 535
Mar 2016: 1355
Nov 2016: 555
Jan 2018: 1481
Dec 2018: 1053
Dec 2019: 2012
Oct 2020: 1591
Jan 2022: 2281
TOTAL: 11,278
TOTAL after deduplication and first assessment (if performed) by Cochrane Dementia and Cognitive Improvement Group Information Specialists Jul 2011: 69
Jun 2015: 247
Mar 2016: 43
Nov 2016: 40
Jan 2018: 72
Dec 2018: 136
Dec 2019: 1557
Oct 2020: 1231
Jan 2022: 1709
TOTAL: 5104