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. 2023 Jan 3;2023(1):CD011881. doi: 10.1002/14651858.CD011881.pub2

ChiCTR2000039991.

Study name The effectiveness of light therapy on sleep quality, cognitive function, BPSD, and depression in patients with mild cognitive impairment and dementia: a randomized controlled trial
Methods Randomised controlled trial
Participants Inclusion criteria:
  • simple MMSE ≥ 24 points or MoCA cut score 23/24 is divided into mild cognitive dysfunction, or meet the ICD‐10 mild and moderate dementia diagnosis

  • can communicate in Mandarin (Taiwan)

  • aged > 65 years

  • complaints of sleep disorders, and PSQI ≥ 5 points

  • regular and stable medication

  • no special eye disease, can accept continuous light

  • living in an institution, the staff can monitor their sleep status, or their coresident family members can assist in monitoring their sleep status

  • must have signed an informed consent form themselves or their family members.


Exclusion criteria:
  • any primary neurological disease that affects the quality of sleep, such as narcolepsy or sleep cessation syndrome

  • diagnosed by a physician with obvious mental illness or communication disorders

  • assessed by the sleep apnoea scale in the Sleep Disorders Questionnaire, females > 26 points, males > 29 points, judged to have sleep apnoea

  • photosensitivity dermatitis in the past

  • diagnosed by a physician with related eye diseases that cannot receive continuously light

  • unsuitable to participate in this course of treatment after being assessed by a physician


Aged: 65–100 years
Gender: both
Interventions Intervention: light therapy
Control: standard light group
Outcomes Sleep quality; cognitive function; behavioural and psychological symptom associated with dementia, BPSD; depression
Starting date 8 February 2020
Contact information kueiru@tmu.edu.tw
Notes Authors did not respond after several contact attempts.