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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2022 Apr 9;129(2):231–240.e2. doi: 10.1016/j.anai.2022.04.003

Figure 1.

Figure 1.

Cartoon representation of the multivalent binding and crosslinking of specific IgE-FcεRI complexes on RBL cell surface by natural dust mite allergen Der p 2 (A) and nanoallergens presenting immunogenic epitopes (B), inducing intracellular signaling cascades resulting in degranulation. Drawings are not to scale.