Figure 3. Semisolid MT correction for CEST-MRF.

(A) Reference dictionary (solid) and reference signal (dashed) are different in the presence of the semisolid MT effect. (B) Signal attenuation due to the semisolid MT effect can be estimated by comparing the reference dictionary and reference signal. (C) The label dictionary is generated by simulating 2-pool Bloch-McConnell equations with known T₁ and T₂ values. (D) The corrected label dictionary can be generated by adding the semisolid MT effect (B) to the dictionary (C). Reproduced with permission from Zhou et al., Magn Reson Med. 2018;80(4):1352-1363.⁶⁰