Fig. 3.

Allelic haplotype mapping to identify the carrier status of the embryos from patient 1. The two breakpoints were identified by analysis of copy number variations from the reference embryos. Subsequently, NGS was used to sequence SNPs flanking the breakpoint for the related embryos and parents. A and B SNP haplotypes were determined successfully for chromosomes 2 and 5, and three balanced diploid embryos (C, D, and E) were free of translocation