Table 4.
Subgroup analysis of renal outcome in a study of effect of HDL-C on renal outcome in patients with INS complicated with SIDM
| Subgroup | Cases | HR (95%CI) | P value | P for interaction |
|---|---|---|---|---|
| Age (years) | 0.022 | |||
| >60y | 18/52 | 1.41 (0.89,2.24) | 0.139 | |
| ≤60y | 16/178 | 1.13 (0.79,1.60) | 0.503 | |
| Baseline hypertension | 0.055 | |||
| Yes | 21/69 | 1.55 (0.99,2.41) | 0.054 | |
| No | 13/161 | 1.18 (0.84,1.68) | 0.343 | |
| Infection | 0.862 | |||
| Yes | 9/31 | 1.16 (0.61,2.23) | 0.650 | |
| No | 25/199 | 1.17 (0.88,1.56) | 0.273 | |
| Focal sclerosis(%) | 0.002 | |||
| > 12 | 19/52 | 1.45 (0.92,2.29) | 0.108 | |
| ≤12 | 15/176 | 1.05 (0.66,1.69) | 0.829 | |
| At least Grade 1 tubulointerstitial damage | 0.002 | |||
| Yes | 11/36 | 1.77 (0.79,3.97) | 0.169 | |
| No | 23/194 | 1.20 (0.90,1.58) | 0.213 |
HDL-C High density lipoprotein cholesterol, INS Idiopathic nephrotic syndrome, SIDM Steroid-induced diabetes mellitus