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. 2023 Jan 3;24:2. doi: 10.1186/s12882-022-03042-9

Table 4.

Subgroup analysis of renal outcome in a study of effect of HDL-C on renal outcome in patients with INS complicated with SIDM

Subgroup Cases HR (95%CI) P value P for interaction
Age (years) 0.022
 >60y 18/52 1.41 (0.89,2.24) 0.139
 ≤60y 16/178 1.13 (0.79,1.60) 0.503
Baseline hypertension 0.055
 Yes 21/69 1.55 (0.99,2.41) 0.054
 No 13/161 1.18 (0.84,1.68) 0.343
Infection 0.862
 Yes 9/31 1.16 (0.61,2.23) 0.650
 No 25/199 1.17 (0.88,1.56) 0.273
Focal sclerosis(%) 0.002
 > 12 19/52 1.45 (0.92,2.29) 0.108
 ≤12 15/176 1.05 (0.66,1.69) 0.829
At least Grade 1 tubulointerstitial damage 0.002
 Yes 11/36 1.77 (0.79,3.97) 0.169
 No 23/194 1.20 (0.90,1.58) 0.213

HDL-C High density lipoprotein cholesterol, INS Idiopathic nephrotic syndrome, SIDM Steroid-induced diabetes mellitus