Table 1.
Baseline characteristics of the study participants.
| Overall | Discovery cohort | Validation cohort | |
|---|---|---|---|
| Number of participants | 1910 | ||
| Included in analyses | 1895 | 1559 (82.3%) | 336 (17.7%) |
| Age in years, median (IQR) | 53 (44-60) | 53 (43-59) | 53 (47-60) |
| Gender, N (%) | |||
| Cis-male | 1594 (84.1%) | 1310 (84.0%) | 284 (84.5%) |
| Cis-female | 288 (15.2%) | 236 (15.2%) | 52 (15.5%) |
| Trans-male | 1 (0.05%) | 1 (0.06%) | 0 (0%) |
| Trans-female | 12 (0.6%) | 12 (0.8%) | 0 (0%) |
| Ethnical ancestry, N (%) | |||
| White | 1430 (75.5%) | 1140 (73.1%) | 290 (86.3%) |
| Black | 192 (10.1%) | 167 (10.7%) | 25 (7.4%) |
| Asian | 87 (4.6%) | 76 (4.9%) | 11 (3.3%) |
| Hispanic | 50 (2.6%) | 48 (3.1%) | 2 (0.6%) |
| Native American | 3 (0.2%) | 1 (0.06%) | 2 (0.6%) |
| Mixed* | 131 (6.9%) | 125 (8.0%) | 6 (1.8%) |
| Unknown | 2 (0.1%) | 2 (0.1%) | 0 (0%) |
| BMI (kg/m2), median (IQR) | 25.0 (22.4-27.7) | 24.9 (22.4-27.6) | 25.5 (22.7-27.9) |
| Smoking status, N (%) | |||
| Current smoker | 559 (29.5%) | 459 (29.4%) | 100 (29.8%) |
| Previous smoker | 571 (30.1%) | 474 (30.4%) | 97 (28.9%) |
| Never smoked | 622 (32.8%) | 516 (33.1%) | 106 (31.5%) |
| Unknown | 143 (7.5%) | 110 (7.1%) | 33 (9.8%) |
*Mixed ethnicity is defined as having at least two grandparents of two separate ethnical ancestries.
BMI, Body Mass Index.