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. 2022 Dec 20;13:982746. doi: 10.3389/fimmu.2022.982746

Table 6.

COVID-19 status and serology measurement at baseline visit.

Overall Discovery cohort Validation cohort
A. Status COVID-19 vaccination at baseline inclusion
Fully vaccinated, N (%) 259 (13.7%) 237 (15.2%) 22 (6.5%)
Positive S-serology measured at baseline visit 257 (13.6%) 235 (99.2%) 22 (100%)
Negative S-serology measured at baseline visit 2 (0.1%) 2 (0.8%) 0 (0%)
Vaccinated but not fully, N (%) 213 (11.2%) 161 (10.3%) 52 (15.5%)
Vaccinated, but unknown how often or when, N (%) 2 (0.1%) 2 (0.1%) 0 (0%)
Unvaccinated, N (%) 1421 (75.0%) 1159 (74.3%) 262 (80.0%)
B. Previous COVID-19 infection at baseline inclusion
Participant not exposed to COVID-19 (enrolled March 2020 or earlier), N (%) 381 (20.1%) 293 (18.8%) 88 (26.2%)
Participants potentially exposed to COVID-19 (enrolled June 2020 or later), N (%) 1514 (79.9%) 1266 (81.2%) 248 (73.8%)
Of participants exposed to COVID-19:
At least one vaccination, N (%) 474 (31.3%) 400 (31.6%) 74 (29.8%)
Evidence of past COVID-19 infection, N (%) 55 (11.6%) 47 (11.8%) 8 (10.8%)
Reported previous positive PCR, N 37 30 7
Previous positive S-serology in own hospital before vaccination, N 21 20 1
No vaccination, N (%) 1040 (68.7%) 866 (68.4%) 174 (70.2%)
Evidence of past COVID-19 infection, N (%) 179 (17.2%) 143 (16.5%) 36 (20.7%)
Previous reported positive PCR, N 40 32 8
Previous positive S-serology in own hospital before vaccination, N 30 30 0
Positive S-serology at baseline visit, N 175 141 34

S, anti-Spike protein; N, Number of Participants. COVID-19, Coronavirus Disease 2019; PCR, Polymerase Chain Reaction.