Table 6.

Results of the Risk of Bias Analysis of Non-Randomized Interventional Studies According to the ROBINS 1 Tool

Publication	Bias Due to Confounding	Bias in Selection of Participants into the Study	Missing Outcome Data	Bias Due to Deviations from Intended Interventions	Bias Due to Missing Data	Bias in Measurement of Outcomes	Bias in Selection of the Reported Result	Overall Risk-of-Bias
Pauly et al, 201548	Low	Low	Moderate	Low	Low	Moderate	Moderate	Moderate
Corden et al, 201637	Critical	Low	Low	Low	Low	Moderate	Low	Critical
Aikens et al, 201553	Moderate	Low	Low	Low	Low	Moderate	Low	Moderate
Gervasoni et al, 201041	Serious	Low	Low	Low	Low	Moderate	Low	Serious
Sajatovic et al, 201545	Moderate	Low	Low	Low	Low	Moderate	Low	Moderate
Levin et al, 201947	Critical	Low	Low	Low	Low	Moderate	Low	Critical