Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 27;15(1):2157697. doi: 10.1080/19490976.2022.2157697

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 3. — Bacterial and functional alterations in gut microbiota of IBS patients with depression. (a) Diversity (Shannon Index) and richness of gut microbiota of IBS patients with depression or without depression in different subtypes, NS means not significant. (b) Principal Coordinates Analysis of gut microbiota composition of IBS patients with depression corresponding IBS patients without depression in different subtypes by Bray-Curtis dissimilarities, the difference among IBS subtypes was assessed by PERMANOVA test. (c) The association between gut microbiota and IBS patients with depression in different subtypes. The association was assessed by the multivariate analysis by linear models (MaAsLin; p < .05, FDR<0.1). (d) MetaCyc pathway differences between IBS patients with depression and those without depression, * p < .05, ** p < .01, *** p < .001, **** p < .0001. In each subtype, an equal number of IBS patients without depression were selected using the established matching algorithm.