Table 2.
Model Summary of Group Comparisons in Terms of PRSs
| Controls | High | Intermediate | Deteriorating | Low | η 2 | Contrasts | Within-patient statisticsa | ||
|---|---|---|---|---|---|---|---|---|---|
| PRS | (N = 836) | (N = 139) | (N = 142) | (N = 77) | (N = 133) | F | P | ||
| SZ | −0.185 −0.25, −0.11 |
0.343 0.18, 0.50 |
0.285 0.12, 0.44 |
0.184 −0.02, 0.39 |
0.362 0.20, 0.52 |
0.059 | L = H = I = D > C | 0.65 | .583 |
| BD | −0.113 −0.18, −0.04 |
0.218 0.06, 0.37 |
0.313 0.15, 0.46 |
0.192 −0.02, 0.40 |
0.084 −0.07, 0.24 |
0.028 | I = H > C = D = L | 1.22 | .301 |
| MD | −0.089 −0.15, −0.02 |
0.025 −0.13, 0.18 |
0.113 −0.04, 0.27 |
0.071 −0.14, 0.28 |
0.303 0.14, 0.46 |
0.017 | L > C = I = D = H | 2 | .112 |
| IQ | 0.072 0.03, 0.14 |
0.015 −0.14, 0.17 |
−0.127 −0.28, 0.03 |
−0.07 −0.29, 0.14 |
−0.268 −0.43, −0.10 |
0.013 | L < C = H = D = I | 1.9 | .123 |
Estimated Marginal Means and 95% CIs. The model is corrected by age, sex, country, and the ten ancestry PC as covariates and weighted by case/control.
High = high-cognitive-functioning; Low = low-cognitive-functioning
aStatistics are relative to within-patient only comparisons by assuming the high-cognitive-functioning group as the baseline category. Between-patient contrasts are represented in the “contrasts” column.