TABLE 1-.

Summary of biomarker trends following burn injury

Article	Osteocalcin	Calcium	Aluminum	Type 1 collagen mRNA	BMP 2	Urine free cortisol	Inflammatory markers	PTH	Vit D	Sclerostin	Magnesium
Klein, 1995 [4]	↓			↓		↑	↑
Klein, 1995 [5]	↓	↓ on admit, rose to normal		↑				Remained stable
Klein, 2004 [7]				↓	↓	↑ with ↓ total bone GRα
Klein, 2002 [10]								↓	↓
Klein, 2004 [11]									↓ 25-D. 1,25- D WNL
Klein, 1993 [17]	↓	↑	↑					↑			WNL
Voruganti, 2005 [20]		↑ with ↑ urinary Zn and Cu
Klein, 1998 [21]		↓						↓			↓
Klein, 2009 [22]		Normal at 6 months postburn						Normal at 6 months post-burn	No difference between groups
Gottschlich, 2017 [26]								No difference between groups	No difference between groups.
Klein, 2015 [27]										↑