TABLE 4.
Physical activity and risk of Alzheimer’s disease and related dementias by race/ethnicity
| Black |
Japanese American |
Latino |
Native Hawaiian |
White |
P-heterogeneity by ethnicity | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | HR (95% CI)a | Cases | HR (95% CI)a | Cases | HR (95% CI)a | Cases | HR (95% CI)a | Cases | HR (95% CI)a | ||
| Moderate/vigorous activity | |||||||||||
| <2.5 hours/week | 566 | 1.00 (ref) | 737 | 1.00 (ref) | 699 | 1.00 (ref) | 116 | 1.00 (ref) | 442 | 1.00 (ref) | |
| 2.5 to <5 hours/week | 616 | 1.01 (0.90–1.13) | 1002 | 0.91 (0.83–1.00) | 468 | 1.05 (0.93–1.18) | 167 | 1.00 (0.78–1.27) | 625 | 0.90 (0.79–1.01) | |
| 5 to <7 hours/week | 416 | 0.95 (0.84–1.09) | 894 | 0.78 (0.71–0.86) | 379 | 1.03(0.90–1.17) | 130 | 0.71(0.55–0.9217) | 633 | 0.82 (0.73–0.93) | |
| 7 to <14 hours/week | 371 | 1.02 (0.89–1.17) | 922 | 0.87 (0.79–0.96) | 309 | 0.91 (0.79–1.04) | 164 | 0.80 (0.62–1.02) | 793 | 0.81 (0.72–0.92) | |
| ≥14 hours/week | 298 | 0.99 (0.86–1.15) | 966 | 0.79 (0.72–0.87) | 270 | 0.93 (0.81–1.0) | 173 | 0.81 (0.64–1.04) | 883 | 0.81 (0.72–0.91) | |
| P-trend | 0.99 | <0.001 | 0.14 | 0.23 | 0.007 | 0.52 | |||||
| Total sitting | |||||||||||
| <5 hours/day | 463 | 1.00 (ref) | 895 | 1.00 (ref) | 699 | 1.00 (ref) | 168 | 1.00 (ref) | 559 | 1.00 (ref) | |
| 5 to <7 hours/day | 516 | 1.11 (0.98–1.26) | 1135 | 1.00 (0.91–1.09) | 495 | 1.01 (0.90–1.13) | 173 | 1.10 (0.89–1.36) | 771 | 0.99 (0.89–1.10) | |
| 7 to <9 hours/day | 450 | 1.02 (0.90–1.16) | 1005 | 0.96 (0.87–1.05) | 342 | 0.86 (0.75–0.98) | 1352 | 0.84 (0.67–1.06) | 821 | 0.97 (0.87–1.08) | |
| 9 to <12 hours/day | 486 | 1.10 (0.96–1.25) | 958 | 0.98 (0.90–1.08) | 339 | 0.92 (0.80–1.05) | 16439 | 0.93 (0.75–1.16) | 780 | 0.93 (0.84–1.04) | |
| ≥12 hours/day | 352 | 1.04 (0.90–1.20) | 528 | 0.93 (0.83–1.03) | 250 | 1.09 (0.94–1.26) | 110 | 0.86 (0.67–1.1026) | 445 | 1.01 (0.89–1.15) | |
| P-trend | 0.61 | 0.21 | 0.94 | 0.12 | 0.70 | 0.45 | |||||
a
Adjusted for age at cohort entry, age at Medicare surveillance start, sex, education, history of hypertension, history of heart disease, history of stroke, history of diabetes, Medicare usage (in-patient and out-patient claims separately, number per year), marital status, smoking status, pack-years of cigarette smoking, body mass index, alcohol consumption, and Healthy Eating Index-2015. For moderate/vigorous activity, further adjusted for total sitting. For total sitting, further adjusted for moderate/vigorous activity.