Figure 6 –

DCFHP-alum immunized NHPs shows a balanced distribution of Th1 and Th2 CD4+ T cell responses. T cells from animals in group A, isolated on the day shown on the x-axis, were stimulated with a peptide pool derived from Wuhan-1 (A) or Omicron BA.1 (B) spike protein and Th1 (top) and Th2 (bottom) cytokines were measured using flow cytometry (SI Fig. 8). Percent of CD4+ T cells that express either Th1 (IL-2,IFNγ or TNFα) (yellows and reds) or Th2 (IL-4) (greys) cytokines following stimulation shows both are elicited following vaccination with DCFHP-alum. Arrow denotes day of boost. (C)-(D) As in panels A-B but with NHPs in group B. NHP identification provided correlate with SI table 1.