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. 2023 Jan 3;80(2):380–391. doi: 10.1007/s12020-022-03281-8

Table 2.

Thyroid function and antibody profile of patients with incident anti-TPO or anti-Tg positivity at reassessment

Patient number Sex/Age On admission COVID-19 treatment 3-month assessment 6-month assessment
TSHa fT4a fT3a Anti-TPOb Anti-Tgb TSHa fT4a fT3a Anti-TPOb Anti-Tgb TSHa fT4a fT3a Anti-TPOb Anti-Tgb
1 M/58 0.55 16 2.9 64.9 2957 IFN + RIB + DEX 0.02 21 7.2c 100.1 2794 1.9 14 5.4 112.2 2819
2 F/61 0.61 19 4.1 44.4 5.1 IFN + RIB 0.45 18 4.7 129.7 5.62 0.60 18 5.1 131.9 5.7
3 F/67 1.3 18 N/A 45.5 4.3 IFN + RIB 1.7 17 5.3 148.2 6.6 1.1 16 6.1 56.8 7.2
4 F/61 1.2 17 3.5 6.9 4.9 IFN + RIB 2.8 20 5.0 141.2 8.3 1.9 16 4.3 27.2 20.0
5 M/51 2.2 16 4.6 97.1 4.8 IFN + RIB 1.7 20 5.6 122.4 3.7 2.8 17 5.7 68.0 6.4
6 M/55 1.6 15 3.3 89.3 21.1 REM 3.7 14 3.7 197.9 38.0 N/A
7 M/21 1.1 17 4.4 99.9 6.6 IFN + RIB 0.47 19 5.2 128.5 9.7 N/A
8 M/45 1.6 13 4.9 82.9 9.0 IFN + REM + DEX 1.6 11 5.1 108.1 6.2 N/A
9 F/62 0.98 14 3.3 198.9 43.5 Nil 1.2 15 4.2 264.3 839 N/A

M male, F female, TSH thyroid-stimulating hormone (mIU/L), fT4 free thyroxine (pmol/L), fT3 free triiodothyronine (pmol/L), anti-TPO anti-thyroid peroxidase antibody (units), anti-Tg anti-thyroglobulin antibody (units), COVID-19 coronavirus disease 2019, IFN interferon beta-1b, RIB ribavirin, REM remdesivir, DEX dexamethasone, N/A not available

Age expressed in years

aReference ranges: TSH 0.35–4.8 mIU/L, fT4 12–23 pmol/L, fT3 3.2–6.5 pmol/L

bPositive anti-TPO defined by >100 units; positive anti-Tg defined by >100 units

cHis anti-TSHR titre was 0.8 IU/L, i.e. negative

Values out of reference ranges are in bold