Table 1.
Genotype and Allele Frequency of DPYD Mutations Found in Jordanians Patient With CRC (N= 80). wt, Wild type; vt, variant
Exon/Intron Number | Identified Variant | Nucleotide (wt/vt) |
Genotype Frequency (wt/wt%) (wt/vt%) (vt/vt%) |
Allele Frequency (wt: vt) N (%) |
---|---|---|---|---|
2 | c.85T>C | C: T | 16(20.0) 18(22.5) 46(57.5) | C: 50 (31.3) T: 110 (68.7) |
14 | - | - | - | - |
22 | - | - | - | - |
13 | c.1740+40A>G | A: G | 18 (22.5) 30 (37.5) 32 (40.0) | A: 66 (41.3) G: 94 (58.7) |
c.1740+39C>T | C: T | 62 (77.5) 15 (18.8) 3 (3.8) | C: 139(86.9) T: 21(13.1) | |
g.97515583_97 | NoinsA: | 70 (87.5) 10 (12.5) 0 (0) | NoinsA: 150 (93.7) insA:10(6.3) | |
515584insA | insA |