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. 2022 Sep;23(9):3061–3069. doi: 10.31557/APJCP.2022.23.9.3061

Table 1.

Genotype and Allele Frequency of DPYD Mutations Found in Jordanians Patient With CRC (N= 80). wt, Wild type; vt, variant

Exon/Intron Number Identified Variant Nucleotide
(wt/vt)
Genotype Frequency
(wt/wt%) (wt/vt%) (vt/vt%)
Allele Frequency (wt: vt)
N (%)
2 c.85T>C C: T 16(20.0) 18(22.5) 46(57.5) C: 50 (31.3) T: 110 (68.7)
14 - - - -
22 - - - -
13 c.1740+40A>G A: G 18 (22.5) 30 (37.5) 32 (40.0) A: 66 (41.3) G: 94 (58.7)
c.1740+39C>T C: T 62 (77.5) 15 (18.8) 3 (3.8) C: 139(86.9) T: 21(13.1)
g.97515583_97 NoinsA: 70 (87.5) 10 (12.5) 0 (0) NoinsA: 150 (93.7) insA:10(6.3)
515584insA insA