Table 2.
The Association between rs1801265 (c.85T>C) and Toxicity to 5-fluorouracil (N=80)
| rs1801265 (c.85T>C) | Total | p-value | |||||
|---|---|---|---|---|---|---|---|
| CC | CT | TT | |||||
| Yes | Count | 5.0 | 14.0 | 35.0 | 54.0 | 0.002 | |
| Toxicity | % of Total | 6.3 | 17.5 | 43.8 | 67.5 | ||
| No | Count | 11.0 | 4.0 | 11.0 | 26.0 | ||
| % of Total | 13.8 | 5.0 | 13.8 | 32.5 | |||
| Total | Count | 16.0 | 18.0 | 46.0 | 80.0 | ||
| % of Total | 20 | 22.5 | 57.5 | 100.0 | |||
P-value< 0.05; Odd Ratio, 0.128 and 95% Confidence Interval: 0.035-0.465