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. 2022 Jul 1;6(3):791–815. doi: 10.1162/netn_a_00241

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© 2022 Massachusetts Institute of Technology

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. For a full description of the license, please visit https://creativecommons.org/licenses/by/4.0/.

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Figure 3. — HIV-associated alterations in error-related DMN suppression and relationships with SN-DMN rsFC strength. (A) People living with HIV (PLWH) had significantly higher error-related default mode network (DMN) activity (i.e., reduced DMN suppression; average NoGo-error β coefficients) than did HIV− participants (F[1, 102] = 5.1, p = 0.026; n = 103). Error-related right central executive network (R.CEN), left CEN (L.CEN, data not displayed), and salience network (SN) activity did not differ between HIV groups (p > 0.3). (B) Resting-state functional connectivity (rsFC) between the SN and DMN did not correlate with error-related DMN (r(83) = −0.03, p = 0.8), R.CEN (r(83) = −0.2, p = 0.07), L.CEN (r(83) = −0.1, p = 0.2; data not shown), or SN activity (r(83) = −0.2, p = 0.07). Unstandardized residuals are plotted after regressing out effects of covariates. Error bars = standard error of the mean.