Table 5.
Univariate and multivariate regression analyses identifying predictors of the long-term target lesion failure (TLF).
| Univariate analysis; hazard ratio (95% CI) | p value | Multivariate analysis; hazard ratio (95% CI) | p value | |||
|---|---|---|---|---|---|---|
| Age | 1.02 | (0.99–1.04) | 0.180 | |||
| Male sex | 1.23 | (0.79–1.91) | 0.367 | |||
| DM | 1.763 | (1.19–2.59) | 0.004 | 1.47 | (0.99–2.18) | 0.056 |
| HTN | 0.564 | (0.33–0.98) | 0.041 | 0.53 | (0.31–0.93) | 0.026 |
| Smoking | 1.275 | (0.86–1.91) | 0.235 | |||
| Dyslipidemia | 1.09 | (0.72–1.65) | 0.696 | |||
| CKD | 1.69 | (1.07–2.69) | 0.025 | 1.72 | (1.08–2.74) | 0.023 |
| EF < 50% | 1.78 | (1.20–2.63) | 0.004 | 1.59 | (1.07–2.34) | 0.023 |
| CTO lesion | 1.82 | (1.02–3.26) | 0.044 | 2.04 | (1.13–3.69) | 0.018 |
| Multivessel disease | 1.74 | (0.88–3.45) | 0.110 | |||
| Periprocedural MI | 2.72 | (1.46–5.09) | 0.002 | 2.46 | (1.28–4.76) | 0.007 |
| Slow flow | 1.82 | (0.79–4.14) | 0.156 | |||
| Perforation | 1.69 | (0.62–4.58) | 0.306 | |||
| Bifurcation | 1.12 | (0.76–1.654) | 0.562 | |||
| Ostial lesion | 1.41 | (0.94–2.13) | 0.098 | 1.25 | (0.82–1.92) | 0.297 |
| Stent length | 1.00 | (0.99–1.01) | 0.525 | |||
| Bailout RA | 1.08 | (0.73–1.59) | 0.712 | |||
| Early generation DES | 0.957 | (0.62–1.48) | 0.845 | |||
Data are presented as hazard ratio and 95% confidence interval. CAD, coronary artery disease; CKD, chronic kidney disease; CTO, chronic total occlusion; DES, drug-eluting stent; DM, diabetes mellitus; EF, ejection fraction; GFR, glomerular filtration rate; HTN, hypertension; MI, myocardial infarction; PCI, percutaneous coronary intervention; RA, rotational atherectomy.