Table 1.
Amino acid residues with induced mutations in small GTPases
| Symbol | Mutation | Symbol | Mutation | Symbol | Mutation | ||
|---|---|---|---|---|---|---|---|
| Arf subfamily | Rrad | P100V | Rab27A | Q78L | |||
| Arl3 | Q71L | Rem1 | P89V | Rab27B | Q78L | ||
| Arl2 | Q70L | Rem2 | Q173L | Rab28 | Q72L | ||
| Arf5 | Q71L | Diras1 | G16V | Rab30 | Q68L | ||
| Arf4 | Q71L | Diras2 | G16V | Rab32 | Q85L | ||
| Arf3 | Q71L | Diras3 | Q95L | Rab33A | Q95L | ||
| Arf1 | Q71L | RasD1 | S33V | Rab33B | Q92L | ||
| Arf6 | Q67L | RasD2 | S30V | Rab34 | Q111L | ||
| TRIM23 | K458I | RasL10B | I63L | Rab35 | Q67L | ||
| Arl1 | Q71L | RasL10A | P13V | Rab36 | Q182L | ||
| Arl5B | Q70L | NkiRas1 | WT | Rab37 | Q82L | ||
| Arl5A | Q70L | NkiRas2 | WT | Rab38 | Q69L | ||
| Arl14 | Q68L | Rab subfamily | Rab39A | Q72L | |||
| Arl11 | Q67L | Rab1A | Q70L | Rab39B | Q68L | ||
| Arl4A | Q79L | Rab1B | Q67L | Rab40A | Q73L | ||
| Arl4C | Q72L | Rab2A | Q65L | Rab40B | Q73L | ||
| Arl4D | Q80L | Rab2B | Q65L | Rab40C | Q73L | ||
| ArfRP1 | Q79L | Rab3A | Q81L | Rab41 | Q90L | ||
| Arl6 | Q73L | Rab3B | Q81L | Rab42 | H74L | ||
| Arl13B | G75L | Rab3C | Q89L | IFT27 | P14V | ||
| Sar1a | H79G | Rab3D | Q81L | RasEF | Q600L | ||
| Sar1b | H79G | Rab4A | Q72L | Rho subfamily | |||
| Arl15 | A86L | Rab4B | Q67L | Rac3 | Q61L | ||
| Arl16 | C86L | Rab5A | Q79L | Rac1 | Q61L | ||
| Arl8A | Q75L | Rab5B | Q79L | Rac2 | Q61L | ||
| Arl8B | Q75L | Rab5C | Q80L | RhoG | Q61L | ||
| Arl10 | S132L | Rab6A | Q72L | Cdc42 | Q61L | ||
| Arl9 | S9L | Rab6B | Q72L | RhoJ | Q79L | ||
| Ras subfamily | Rab6C | Q72L | RhoQ | Q67L | |||
| Rit1 | G30V | Rab7A | Q67L | RhoU | Q107L | ||
| Rit2 | G29V | Rab7B | Q67L | RhoV | Q89L | ||
| Rap2C | G12V | Rab7L1 | Q67L | RhoB | Q63L | ||
| Rap2A | G12V | Rab8A | Q67L | RhoC | Q63L | ||
| Rap2B | G12V | Rab8B | Q67L | RhoA | Q63L | ||
| Rap1B | G12V | Rab9A | Q66L | RhoF | Q77L | ||
| Rap1A | G12V | Rab9B | Q66L | RhoD | Q75L | ||
| Rras2 | G23V | Rab10 | Q68L | Rnd2 | WT | ||
| Rras | G38V | Rab11A | S20V | Rnd3 | WT | ||
| Mras | G22V | Rab11B | S20V | Rnd1 | WT | ||
| Kras | G12V | Rab12 | Q101L | RhoH | WT | ||
| Nras | G12V | Rab13 | Q67L | RhoBTB2 | WT | ||
| Hras | G12V | Rab14 | Q70L | RhoBTB1 | WT | ||
| RalB | G23V | Rab15 | Q67L | Ran/unclassified | |||
| RalA | G23V | Rab17 | Q77L | Ran | Q69L | ||
| Eras | Q99L | Rab18 | Q67L | IFT22 | C12V | ||
| RhebL1 | Q64L | Rab19 | Q76L | SRPRB | C73V | ||
| Rheb | Q64L | Rab21 | Q78L | RhoT1 | P13V | ||
| Rerg | Q64L | Rab22A | Q64L | RhoT2 | A13V | ||
| RasL12 | R29V | Rab22B | Q65L | RabL3 | S15V | ||
| RasL11A | G36V | Rab23 | Q68L | RabL2A | Q80L | ||
| RasL11B | S42V | Rab24 | S67L | RabL2B | Q80L | ||
| RergL | Q62L | Rab25 | S21V | Rab20 | R59L | ||
| Gem | Q84V | Rab26 | Q123L |