Table 4.3.
Assessment of hypoglycemia risk
| Factors that increase risk of treatment-associated hypoglycemia |
| • Use of insulin or insulin secretagogues (i.e., sulfonylureas, meglitinides) |
| • Impaired kidney or hepatic function |
| • Longer duration of diabetes |
| • Frailty and older age |
| • Cognitive impairment |
| • Impaired counterregulatory response, hypoglycemia unawareness |
| • Physical or intellectual disability that may impair behavioral response to hypoglycemia |
| • Alcohol use |
| • Polypharmacy (especially ACE inhibitors, angiotensin receptor blockers, nonselective β-blockers) |
| • History of severe hypoglycemic event |
| In addition to individual risk factors, consider use of comprehensive risk prediction models (233). |