Extended Data Fig. 2. Distinct transcription signatures in PMN-MDSC and TAMs of Shp2f/fLysMCre tumor-bearing mice compared to Shp2f/f tumor-bearing mice.
a, b, Shp2f/fLysMCre and Shp2f/f mice were injected with MC17-51 cancer cells and 15 days later, PMN-MDSC (a) were isolated from the spleens, TAMs (b) were isolated from tumors, and RNA-seq was performed followed by pathway enrichment analysis of DEG. Heat maps of DEG for enriched pathways are shown. Differential gene expression analysis was performed using DESeq2.