This is the first study that demonstrates the actual feasibility of caffeine administration in the delivery room without interfering with infants’ postnatal assistance.

For the first time we described the feasibility of enteral administration of caffeine in the delivery room. The effectiveness of the procedure was confirmed by the measurement of caffeine blood level.

In some patients, the caffeine therapeutic range was not reached, and this raises the question of which dose is the most effective to prevent MV.