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. 2023 Jan 2;33(1):46–54. doi: 10.1038/s41422-022-00751-6

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Fig. 2 — a Three interfaces formed by MRAP1 contacting MC2R and ACTH. b–d Detailed interactions between MRAP1 iJM motif and MC2R (b), between MRAP1 eJM motif and MC2R (c), and between MRAP1 and ACTH (d), highlighted in the blue, black and red frames in a, respectively. e–g cAMP responses of ACTH-stimulated MC2R–MRAP1 WT or mutants in the interacting interfaces of b–d.