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. 2022 Dec 21;9:1022889. doi: 10.3389/fmed.2022.1022889

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Copyright © 2022 Deng, Parthasarathy, Marani, Bordeaux, Lee, Trinh, Cornman, Kambala, Pritchard, Chen, Sutaria, Oladipo, Kwatra, Alphonse and Kwatra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene set enrichment analysis of dysregulated genetic pathways in prurigo nodularis (PN) and atopic dermatitis (AD) skin. (A) Gene set enrichment analysis (GSEA) for selected significant immune pathways in PN lesional vs. AD lesional skin. (B) GSEA for selected significant immune pathways in PN non-lesional vs. AD non-lesional skin. FC, fold change; FDR, false discovery rate p-values; NES, normalized enrichment score.