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. 2022 Dec 21;9:1022889. doi: 10.3389/fmed.2022.1022889

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Copyright © 2022 Deng, Parthasarathy, Marani, Bordeaux, Lee, Trinh, Cornman, Kambala, Pritchard, Chen, Sutaria, Oladipo, Kwatra, Alphonse and Kwatra.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemistry (IHC) analysis of nerve growth factor (NGF) in prurigo nodularis (PN) and atopic dermatitis (AD) skin. (A–D) Representative NGF IHC staining in PN lesional, PN non-lesional, AD lesional, and AD non-lesional skin, respectively. Panels (A,C) 10×. Panels (B,D) 15×. (E) Quantification of the percentage of NGF-positive cells in lesional PN vs. lesional AD skin. (F) Quantification of the percentage of NGF-positive cells in non-lesional PN vs. non-lesional AD skin. *p < 0.05. The symbol “●” represents the percentage of positive cells for an individual sample.