Table 3.
Test | Chlorpheniramine Mean±SEM | Levocetirizine Mean±SEM | Fexofenadine Mean±SEM | |||||||||||||||
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Baseline | 1 Week | 4 Week | Baseline | 1 Week | 4 Week | Baseline | 1 Week | 4 Week | ||||||||||
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Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | |
Epworth sleepiness scale | 4.41 | 0.68 | 5.82* | 0.66 | 5.41 | 0.72 | 3.39 | 0.56 | 4.70* | 0.57 | 4.65@ | 0.46 | 4.65 | 0.70 | 4.25 | 0.63 | 4.00@ | 0.57 |
Brief mood introspection scale (BMIS) Pleasant unpleasant score | 53.77 | 1.46 | 54.00 | 0.91 | 52.91 | 0.64 | 54.70 | 1.60 | 54.13 | 1.5 | 52.30#@ | 1.26 | 54.85 | 0.87 | 55.45 | 0.84 | 53.00# | 0.80 |
BMIS arousal calm score | 28.32 | 0.78 | 27.95 | 0.84 | 25.50#@ | 0.70 | 28.52 | 0.47 | 27.65 | 0.76 | 27.83 | 0.72 | 27.85 | 0.45 | 29.05 | 0.75 | 26.05# | 0.79 |
BMIS positive tired score | 22.23 | 0.52 | 21.64 | 0.46 | 19.95#@ | 0.51 | 23.22 | 0.59 | 21.78* | 0.62 | 20.87@ | 0.72 | 22.75 | 0.47 | 22.45 | 0.42 | 20.20#@ | 0.71 |
BMIS negative relaxed score | 8.86 | 0.87 | 8.18 | 0.63 | 7.82 | 0.47 | 8.52 | 0.68 | 8.43 | 0.67 | 8.61 | 0.63 | 8.10 | 0.38 | 8.20 | 0.55 | 7.40 | 0.52 |
Footnote: Paired sample t-test was used for intragroup comparison and ANOVA followed by post hoc analysis was used for intergroup comparison. In intragroup comparison, * depicts significance at 1 week as compared to baseline, # depicts significance at 4 week as compared to 1 week, and @ depicts significance at 4 week as compared to baseline. In intergroup comparison (shaded boxes represent comparison groups showing significance), $ depicts significance at 1 week and ^ depicts significance at 4 week