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. 2022 Oct 31;11(10):5909–5917. doi: 10.4103/jfmpc.jfmpc_77_22

Table 4.

Effects of bepotastine on memory, psychomotor functions, sleep and mood

Baseline 1 week 4 week



Mean SEM Mean SEM Mean SEM
Remote memory 8 0 7.39* 0.231 7.94# 0.056
Recent memory 4.89 0.076 4.94 0.056 4.94 0.056
Mental Balance 4.5 0.55 4.28 0.636 4.22 0.613
Attention and concentration 3.78 0.552 3.5 0.414 3.83 0.493
Delayed recall 8.44 0.372 8.33 0.45 8.5 0.345
Immediate recall 6.5 0.682 6.17 0.612 6.72 0.516
Verbal retention of similar pairs 3.83 0.167 4.11 0.159 4.11 0.196
Verbal retention of dissimilar pairs 8.89 0.816 9.06 0.906 10#,@ 0.82
Visual retention 6.83 0.48 7.5 0.525 7.78 0.558
Recognition 8.06 0.521 8.22 0.552 8.56#,@ 0.55
PGIMS score 63.72 1.97 63.5 2.43 66.61# 2.416
Single letter cancellation test 22.17 1.253 23.72 1.643 24 1.563
Digit letter substitution test 19.78 1.689 19.94 2.173 20.17 1.844
Choice reaction time audio 1.51 0.09593 1.37507 0.076186 1.39339^ 0.074468
Choice reaction time video 1.4 0.11132 1.37507 0.076186 1.39339 0.074468
Hand steadiness test 61.15 9.42 58.2 9.86 53.35 @ 8.01
Critical flicker fusion threshold at 20 Hz 47.64 0.14 47.78 0.19 47.64 0.14
Critical flicker fusion threshold at 50 Hz 47.64 0.14 47.64 0.14 47.64 0.14
Epworth sleepiness scale 4.72 0.69 5.89 0.69 5.06 0.569
Pleasant unpleasant score 53.22 2.209 54.39 1.753 53.72 1.604
Arousal calm score 28.94 0.857 27.11* 0.766 26.67@ 0.804
Positive tired score 22.5 0.857 21.72 0.804 20.89@ 0.9
Negative relaxed score 9.11 0.976 7.67 0.695 7.44 0.677

Footnote: Paired sample t-test was used for intragroup comparison. Here, * depicts significance at 1 week as compared to baseline, # depicts significance at 4 week as compared to 1 week, @ depicts significance at 4 week as compared to baseline. The shaded area represents the difference observed in intragroup comparison and ^ depicts significance at 4 week