Table 3.

Outcomes at data cutoff.

	N (%)
Treatment status	17
Patients on treatment	7 (42)
Patients off treatment	10 (59)
Central nervous system (CNS) progressive disease	2 (12)
Extracranial progressive disease	4 (24)
CNS + extracranial progressive disease	1 (6)
Radiation necrosis	1 (6)
Adverse effect	1 (6)
Patient choice	1 (6)
Median months on treatment	8.9 (1.3–16.2)
Best extracranial response	11
Complete response	0 (0)
Partial response	5 (45)
Stable disease	5 (45)
Progressive disease	1 (5)
Best CNS response	15
Complete response	0 (0)
Partial response	11 (73)
Stable disease	3 (20)
Progressive disease	1 (5)
Best CNS response in active BCBM	10
Complete response	0 (0)
Partial response	7 (70)
Stable disease	3 (30)
Progressive disease	0 (0)