TABLE 1.

Virulence of S. suis library and strains in germfree pigs

Strain	No. of pigs	Dose of S. suis (CFU)	Mortalitya (%)	Mean no. of days until death	Morbidityb (%)	Clinical index of the group		Fever indexe	Leukocyte indexf	No. of pigs in which S. suis was isolated from:
						Specificc symptoms	Nonspecificd symptoms			CNS	Serosae	Joints
S735(pCOM-L)	4	107	100	4	100	69	91	25	NAg	3	2	3
	4	108	75	7	100	50	69	20	17	2	1	2
S735(pCOM-V10)	5	106	100	1	100	100	100	54	4	5	5	5
S735(pCOM1)	4	106	25	12	25	2	11	6	80	1	1	2
S735(pCOM-V10)	5	106	100	1	100	100	100	60	NA	5	5	5
S735(pCOM-V735)	5	106	20	15	100	40	26	17	52	1	1	1
S735(pCOM1)	5	106	20	16	60	11	9	11	20	1	0	0
24(pCOM-V10)	5	106	100	2	100	50	66	42	29	3	3	5
24(pCOM-V735)	4	106	25	15	100	40	30	17	18	1	0	0
24(pCOM1)	5	106	20	15	20	2	14	6	21	1	0	0

^aPercentage of pigs that died due to infection or had to be killed for animal welfare reasons. 

^bPercentage of pigs with specific symptoms. 

^cPercentage of observations for the experimental group in which specific symptoms (ataxia, lameness of at least one joint, and/or stillness) were observed. 

^dPercentage of observations for the experimental group in which nonspecific symptoms (loss of appetite and/or depression) were observed. 

^ePercentage of observations for the experimental group of a body temperature of >40°C. 

^fPercentage of blood samples for the experimental group in which the concentration of granulocytes was >10¹⁰/liter. 

^gNA, not applicable.