Table 2.

Studies reporting a lack of association between MGD and CLs. The Table summarizes research studies reporting a lack of relationship between CL wear and MGD. Columns describe study authors (first column), subjects and controls including their age range (second column), and outcome parameters divided into morphological (columns 3-4), functional (columns 5-13), subjective (column 14), and other measures (last column).

Study		Subjects	Assessment
			Morphology					Functional																		Other
			Meibography			Slit lamp -lid margin		MG expression		Fluorescein staining- cornea, conjunctiva		TBUT / NITBUT		Schirmer test		Tear meniscus height		Tear osmolarity		Tear evaporation rate		Lipid layer assessment		Blink rate		Questionnaire		Other
Hom et al.35		CL wearers (N=162) non–CLs wearers (N=236) age: <10 - >60				✓		✓
Marren36		CL wearers (N=20) non–CLs wearers (N=30) age: 22 – 35				✓		✓		✓
Pucker et al.39		CL wearers (N=70) non–CLs wearers (N=70) age: 18 - 43	✓			✓		✓		✓		✓		✓		✓		✓								✓
Ong38		CL wearers (N=81) non–CLs wearers (N=150) age: 15 - 40						✓
Nichols and Sinnott7		CL wearers (N=360) Mean age: 31.1	✓			✓				✓						✓		✓				✓		✓		✓
Na et al.37		CL wearers (N=58) age: 7- 18	✓			✓				✓		✓		✓				✓								✓		Evaluation of inflammation MG width
Pucker et al.40		CL wearers (N=112) (56 CL dropout vs. 56 successful CL wearers) age: 18-45	✓			✓		✓				✓														✓		MG width