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. 2022 Dec 9;20(1):370–382. doi: 10.1021/acs.molpharmaceut.2c00668

Table 1. Hepatocyte Clearance.

compound ID N clearance (μL/min/million cells) half-life (min)
BCV C16 9.73 142
NPP-662 C10 18.8 73.8
NPP-663 C10 22.2 62.4
NPP-664 C12 60.6 22.9
NPP-666 C12 14.7 94.3
NPP-667 C14 154 9.01
NPP-669 C13 6.85 202
NPP-670 C12 33.3 41.6