Table 1.

Clinicopathological profiles of patients with GC from Eastern Europe, China, and Japan

	Eastern Europe		China		Japan
	n = 188		n = 133		n = 268		p-valuec
Age
Mean	62.6		61.2		63.7		0.02
Range	22-98		40-77b		25-85
	n	%	n	%	n	%	p-valued
Sex
Male	190	66.2	96	74.4	166	69.7
Female	97	33.8	33	25.6	72	30.3
Unknown	1a		4		30
Subtype
Diffuse	127	44.1	69	51.9	150	56.0	2 × 10−5
Intestinal	161	55.9	60	45.1	83	31.0
Others or unknown			4	3.0	35	13.1

^aThe sex information was not available in one case from Eastern Europe

^bThe ages of two Chinese cases (one male, one female) were unknown

^c P-value of the t-test for the ages between China and Japan

^d P-value of the χ² test for histological subtypes among the three groups: Eastern Europe, China, and Japan