Table 2.

TP53 mutation status in Eastern Europe, China, and Japan (exons 4 to 8)

TP53 mutation	Eastern Europe		China		Japan		P-valuea	P-valueb
	n	%	n	%	n	%
Mutant (n = 285, 41.4%)	85	29.5	76	57.1	124	46.3	7 × 10−8	9 × 10−8
Wild type (n = 404, 58.6%)	203	70.5	57	42.9	144	53.7

^a P-value of the χ² test for the TP53 mutation prevalence among the three groups: Eastern Europe, China, and Japan

^b P-value of the χ² test for the TP53 mutation prevalence between Eastern Europe and East Asia