Table 3.
Echocardiographic parameters at baseline and after 6 months of therapy with sac/val.
| Baseline | Follow-up | P | |
|---|---|---|---|
| Variables | (n=132) | (n=132) | |
| LAVI,mL/m2 | 49.8 ±13.7 | 46.1 ± 12.0 | 0.001 |
| LVEDV/BSA, mL/m2 | 89.6 ±9.8 | 87.8 ±8.4 | <0.0001 |
| LVESV/BSA, mL/m2 | 61.0 ±7.1 | 57.3 ± 5.9 | <0.0001 |
| LVEF, % | 31.9 ± 1.4 | 34.7 ±1.6 | <0.0001 |
| CI mL/min/m2 | 1675.6 ±199.9 | 1856.6 ± 212.9 | <0.0001 |
| E/e' ratio | 17.4 ±3.5 | 15.9 ±2.8 | <0.0001 |
| GLS, % | -7.9 ±1.7 | -9.0 ±1.4 | <0.0001 |
| RVOT, cm | 2.6 ±0.4 | 2.1 ±0.4 | <0.0001 |
| RAA, cm2 | 20.5 ± 2.8 | 19.3 ± 2.3 | <0.0001 |
| TAPSE, mm | 16.3 ±1.1 | 17.1 ±1.7 | <0.0001 |
| S-PAP, mmHg | 44.5 ± 6.6 | 41.5 ±6.6 | <0.0001 |
| TAPSE/S-PAP, mm/mmHg | 0.37 ± 0.06 | 0.42 ± 0.08 | <0.0001 |
| IVC, mm | 20.2 ±1.3 | 19.1 ±3.3 | <0.0001 |
Abbreviations: LAVI, left atrium volume index; LVEDV, left ventricular end-diastolic volume; BSA, body surface area; LVESV, left ventricular end-systolic volume; LYEF, left ventricular ejection fraction; CI, cardiac index; GLS, left ventricular global longitudinal strain; RVOT, right ventricular outflow tract; RAA, right atrium area; TAPSE, tricuspid annular plane excursion; S-PAP, systolic pulmonary arterial pressure; IVC, inferior vena cava.