Table.
Clinical and baseline echocardiographic characteristics of the 408 HCM patients.
| HCM patients with LVf >7.5 mm Hg/ml (n=86) | HCM patients with LVf ≤7.5 mm Hg/ml (n=322) | p-value | |
|---|---|---|---|
| Age (years) | 48±15 | 46±15 | 0.297 |
| Females | 50 (58%) | 87(27%) | <0.0001 |
| Diabetes | 14(16%) | 20 (6%) | 0.003 |
| NYHA class | 1.8±0.7 | 1.4±0.7 | 0.0001 |
| Beta-blocker | 70 (81%) | 186 (58%) | <0.0001 |
| Calcium-channel blocker | 16(19%) | 29 (9%) | 0.012 |
| Diuretics | 16(19%) | 26 (8%) | 0.004 |
| Left atrial diameter (mm) | 47±7 | 43±7 | <0.0001 |
| LV MWT (mm) | 23±6 | 22±6 | <0.0001 |
| LV ejection fraction (%) | 75±6 | 67±7 | <0.0001 |
| Mitral regurgitation grade | 1.2±0.7 | 0 . 7 ± 0.7 | <0.0001 |
| E/e' | 10±5 | 8±5 | 0.005 |
Data are expressed as mean value ±SD or number (%) of patients.
Abbreviations: E: early mitral inflow velocity; e': early diastolic mitral annular velocity; HCM: hypertrophic cardiomyopathy; LV: left ventricular; MWT: maximal wall thickness; NYHA: New York Heart Association