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Quantification of nitrite released by DC 2.4 upon 48 h of exposure to different treatment groups. Nitrite released by dendritic cells pulsed with spike GP MPs + Alhydrogel® MPs + AddaVax™ MPs was significantly higher as compared to spike suspension, spike GP MPs and spike GP + Alhydrogel® MPs. Data expressed as a mean ± SEM was analyzed using one-way ANOVA followed by post hoc Tukey’s multiple comparison test. ***p < 0.001, ****p < 0.0001.
