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Spike GP specific-antibody levels in serum for IgG2a measured in vaccinated and unvaccinated mice. Serum was analyzed using ELISA at dilution 1:50. Data are expressed as mean ± SEM analyzed using two-way ANOVA followed by post hoc Tukey’s multiple comparison test- ns- non significant, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.
