Table 2.
Outcome | Contrast extravasation (n = 61) | No contrast extravasation (n = 111) | p value |
---|---|---|---|
Primary outcome | |||
Admission fibrinogen, median (IQR), mg/dL | 203 (167.5–260.5) | 251 (205–303) | 0.0007 |
Secondary outcome | |||
No. of patients within 24 h of fresh frozen plasma transfusions, no. (%) | 36 (59.0) | 21 (18.9) | <0.0001 |
Minimum fibrinogen level within 24 h of admission, median (IQR), mg/dL | 148 (102.5–209.5) | 234 (184–273) | <0.0001 |
Admission platelet count, median (IQR), × 103/μL | 197 (152.5–235) | 220 (176–257) | 0.01 |
Admission PT-INR, median (IQR) | 1.08 (1.01–1.18) | 1.06 (1.01–1.13) | 0.22 |
Admission aPTT, median (IQR), sec | 29 (25–35) | 27 (25–30) | 0.03 |
Admission FDP, median (IQR), μg/mL | 92.2 (47.8–256.0) | 25.3 (9.7–52.5) | <0.0001 |
Admission D-dimer, median (IQR), μg/mL | 24.0 (15.3–64.8) | 8.69 (3.19–18.5) | <0.0001 |
No. of patients within 24 h of transfusions, no. (%) | |||
Red blood cell | 32 (52.5) | 21 (18.9) | <0.0001 |
Platelet concentrate | 14 (23.0) | 3 (2.7) | <0.0001 |
No. of units within 24 h of transfusions, median (IQR), units | |||
Red blood cell | 2 (0–10) | 0 (0–0) | <0.0001 |
Fresh frozen plasma | 6 (0–16) | 0 (0–0) | <0.0001 |
Platelet Concentrate | 0 (0–0) | 0 (0–0) | <0.0001 |
IQR, interquartile range; PT-INR, prothrombin time/international normalized ratio; aPTT, activated partial thromboplastin time; FDP, fibrinogen degradation products.