Table 2.

Comparison of antiviral activities of alkaloids and standard drugs

S.N	Virus	Alkaloid	Inhibitory concentration	Standard drug	Inhibitory concentration	Ref.
1	HBV	5,6-Dihydro-6-methoxynitidine	0.2 μmol/mL	Lamivudine	1.0 μmol/mL	[75]
2	HBV	5-Methoxydictamnine	0.2 μmol/mL	Lamivudine	1.0 μmol/mL	[75]
3	CHIKV	Harringtonine	EC50 = 0.24 μM	Rottlerin	More than 10 μM	[16]
4	CHIKV	Harringtonine	EC50 = 0.24 μM	Ribavirin	EC50 = 2.05 μM	[16]
5	HSV	Yohimbine	0.8 µg/mL	Acyclovir	1.6 µg/mL	[25]
6	HSV	Vincamine	0.8 µg/mL	Acyclovir	1.6 µg/mL	[25]
7	HSV	Atropine	0.8 µg/mL	Acyclovir	1.6 µg/mL	[25]
8	HSV	Trigonelline	0.4 µg/mL	Acyclovir	1.6 µg/mL	[25]
9	PI-3	Capsaicin	0.2 µg/mL	Oseltamivir	1.6 µg/mL	[25]
10	PI-3	Allantoin	0.4 µg/mL	Oseltamivir	1.6 µg/mL	[25]
11	CV-B3	(−)-12-Hydroxyoxysophocarpine	IC50 = 26.62 µM	Ribavirin	IC50 = 1197.58 µM	[92]
12	IV	Berberine	IC50 = 0.025 g/L	Ribavirin	IC50 = 0.051 g/L	[19]