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. 2022 Jun 25;43(17):5167–5179. doi: 10.1002/hbm.25992

FIGURE 3.

FIGURE 3

Correlation between pain intensity ratings and S1 responses to laser stimulation. (a) S1 activity maps reflecting subjective ratings of laser‐evoked and spontaneous pain. Subjective ratings of laser‐evoked pain were positively correlated with activations of contralateral SS1 in HC (first panel). Subjective ratings of laser‐evoked pain were positively correlated with activations of bilateral IS1 in PHN patients (second panel). Subjective ratings of spontaneous pain assessed by SF‐MPQ were positively correlated with activations of the right SSI in PHN patients (third panel). Positive brain activity maps of both groups were superimposed on the S1 anatomical template (fourth panel). Yellow mark, S1 anatomical template; green mark, positive brain activity map identified by subjective ratings of laser‐evoked pain in HC; red mark, positive brain activity map identified by subjective ratings of laser‐evoked pain in PHN patients; purple mask, positive brain activity map identified by subjective ratings of spontaneous pain in PHN patients. (b) Scatter plots show the correlations between subjective ratings of pain and responses in S1.